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Research Article | DOI: https://doi.org/CCSRR-RA-25-40

Comparative Studies on Lipid Profile in Both Obese and Lean Subjects in Imo State

Oparaocha Divinegift Chinonso , H.U. Nwanjo , D.C. Nwosu , Nnodim Johnkennedy *

Department of Medical Laboratory Science, Imo State University Owerri Nigeria

*Corresponding Author: Nnodim Johnkennedy, Department of Medical Laboratory Science, Imo State University Owerri Nigeria

Citation: Oparaocha Divinegift Chinonso, H.U. Nwanjo, D.C. Nwosu, Nnodim Johnkennedy (2025). Comparative Studies on Lipid Profile in Both Obese and Lean Subjects in Imo State, J Clinical Case Studies and Review Reports. 2(5) 40, DOI: CCSRR-RA-25-40

Copyright: Nnodim Johnkennedy, et al © (2025). This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Received: 28 August 2025 | Accepted: 05 September 2025 | Published: 17 September 2025

Keywords: lipid profile; obese, lean ; Imo State

Abstract

This study was carried out to compare the levels of lipid profiles in both obese and lean subjects in patients attending Federal Medical Center, Owerri. Eighty (80) subjects including male and female who were within the age range of 25-50 years attending the outpatient department at Federal Medical Center, Owerri were recruited for the study and they were divided into two groups of forty (40) obese and forty (40) lean subjects. Data obtained was analyzed using Statistical Package for Social Sciences (SPSS) version 21.  Values was expressed as mean±standard deviation. The student t-test was used to compare the parameters (at level of significance 0.05). P< 0.05 was considered as statistically significant and P>0.05 was considered not statistically significant. The mean values of serum total cholesterol (216.48±28.42mg/dl), triglyceride (165.5±18.79 mg/dl) and LDL(155.15±10.67mg/dl) was significantly decreased in obese subjects while the mean values of serum HDL(45.68±7.47mg/dl) was significantly decreased in obese subjects. The mean values of serum total cholesterol, triglyceride and LDL was significantly increased in obese male (162.95±20.29mg/dl, 156.95±18.34mg/dl and 84±7.36mg/dl) and female(200.15±16.69mg/dl, 165.25±10.36mg/dl and 125±13.86mg/dl) subjects while serum HDL was significantly decreased in obese male(47.7±5.14mg/dl) and female(42.0±6.89mg/dl) subjects when compared with the control subjects at p<0.05 respectively. The mean value of serum total cholesterol, triglycerides and LDL was significantly increased while HDL was significantly decreased in those within the age range of 25-35 years when compared with the mean value of total cholesterol, triglycerides, LDL and HDL in those between 36-50 years at P<0.05. In conclusion, Lipid profile may serve as a biomarker in obesity and it makes the obese individuals prone to several cardiovascular diseases.

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